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https://w3id.org/np/RAsz8j_6fRD5SpY1o_atGsPpQjMNi-gXq95Nlv-zTU0P0

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Content

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sub:Head {
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sub:assertion {
  <https://w3id.org/delphi/resource/claim/buehler-2009-tropocollagen-sequencing-01>
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    dc:description "Variations in the amino-acid motif of tropocollagen severely change its elastic behaviour, producing softening or stiffening, as shown for four model sequence motifs from human type I collagen.";
    dc:type "simulation-result";
    <http://www.w3.org/2000/01/rdf-schema#label> "Amino-acid motif variation softens or stiffens tropocollagen";
    <https://w3id.org/delphi/ontology/context> "Sebastien G. M. Uzel et al., “Nanomechanical sequencing of collagen: tropocollagen features heterogeneous elastic properties at the nanoscale”, Integrative Biology 1, 452-459 (2009), doi:10.1039/b906864c; Abstract. Scope: Four Gly-X-Y motifs of human type I collagen, single-molecule MD" .
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    dc:bibliographicCitation "Sebastien G. M. Uzel, Markus J. Buehler. Nanomechanical sequencing of collagen: tropocollagen features heterogeneous elastic properties at the nanoscale. Integrative Biology 1, 452-459 (2009). doi:10.1039/b906864c";
    dc:creator "Sebastien G. M. Uzel, Markus J. Buehler";
    dc:date "2009"^^xsd:gYear;
    dc:identifier "doi:10.1039/b906864c", "pmid:20023755";
    dc:title "Nanomechanical sequencing of collagen: tropocollagen features heterogeneous elastic properties at the nanoscale" .
  
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    <https://schema.org/text> "By utilizing a bottom-up computational materiomics approach applied to four model sequence motifs found in human type I collagen, we show that variations in the amino acid motif severely influence the elastic behavior of tropocollagen molecules, leading to softening or stiffening behavior." .
  
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