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Seven loci (y, w, bi, v, m, s, B) looked up by symbol; 1915 map distance for each of the 21 pairs from the book's percentages versus genomic distance between gene midpoints (Mb); Spearman rank correlation.
https://w3id.org/delphi/resource/assessment/morgan1915-04--claim-test
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https://w3id.org/delphi/resource/assessment/morgan1915-04--claim-test
http://www.w3.org/2000/01/rdf-schema#comment
Measured: 0.9662 Spearman rho between 1915 map distance and genomic distance over 21 locus pairs (n = 21, Pearson r 0.972; 7 loci on one chromosome). Interpretation: The 1915 map values are the ones quoted in the claims file from the book (yellow-white 1, white-bifid 5, yellow-bifid 6, white-miniature 33, miniature-Bar 22, vermilion-sable 10, sable-Bar 14), not FlyBase's recombination_loc column, which for most genes is interpolated from cytology and would be circular. The test is one chromosome and seven loci: it tests the law where Morgan stated it, not genome-wide.
https://w3id.org/delphi/resource/assessment/morgan1915-04--claim-test
http://www.w3.org/2000/01/rdf-schema#label
Claim test of morgan1915-04: supports, confidence 0.8
https://w3id.org/delphi/resource/assessment/morgan1915-04--claim-test
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https://w3id.org/delphi/ontology/admissibleDatasets
Planned datasets: flybase-gene-map-table
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Spearman < 0.70: refutes. Between 0.70 and 0.90: mixed. Any of the seven loci not found in the map table with an X-chromosome sequence location: inconclusive.
https://w3id.org/delphi/resource/assessment/morgan1915-04--claim-test
https://w3id.org/delphi/ontology/evidenceAgainst
Seven loci on the X only: it tests the law where Morgan stated it. Genome-wide, recombination rate varies along chromosomes (hotspots, centromere suppression), so the relation is monotone, not linear.
https://w3id.org/delphi/resource/assessment/morgan1915-04--claim-test
https://w3id.org/delphi/ontology/evidenceAgainst
The 1915 map values come from the book's quoted percentages, not from FlyBase's recombination_loc column, which is largely interpolated from cytology.
https://w3id.org/delphi/resource/assessment/morgan1915-04--claim-test
https://w3id.org/delphi/ontology/evidenceAgainst
sable and Bar are resolved through the FlyBase synonym table to Ype (Yippee) and B-H1 (BarH1); the Bar mutation itself is a duplication of 16A with no single coordinate, so B-H1 stands for its position.
https://w3id.org/delphi/resource/assessment/morgan1915-04--claim-test
https://w3id.org/delphi/ontology/expectedObservation
Over the 21 pairs of the seven loci, Spearman rank correlation between 1915 map distance and genomic distance (midpoints of FlyBase sequence locations on X, Release 6) is >= 0.90: supports.
https://w3id.org/delphi/resource/assessment/morgan1915-04--claim-test
https://w3id.org/delphi/ontology/failCriterion
Spearman < 0.70: refutes. Between 0.70 and 0.90: mixed. Any of the seven loci not found in the map table with an X-chromosome sequence location: inconclusive.
https://w3id.org/delphi/resource/assessment/morgan1915-04--claim-test
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supports
https://w3id.org/delphi/resource/assessment/morgan1915-04--claim-test
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If crossing over between two factors increases with their distance apart, the 1915 X-chromosome map distances between yellow, white, bifid, vermilion, miniature, sable and Bar (read from the book's own percentages: y 0, w 1, bi 6, v 32, m 34, s 42, B 56) increase with the genomic distance between those genes.
https://w3id.org/delphi/resource/assessment/morgan1915-04--claim-test
https://w3id.org/delphi/ontology/inferenceMethod
Seven loci (y, w, bi, v, m, s, B) looked up by symbol; 1915 map distance for each of the 21 pairs from the book's percentages versus genomic distance between gene midpoints (Mb); Spearman rank correlation.
https://w3id.org/delphi/resource/assessment/morgan1915-04--claim-test
https://w3id.org/delphi/ontology/passCriterion
Over the 21 pairs of the seven loci, Spearman rank correlation between 1915 map distance and genomic distance (midpoints of FlyBase sequence locations on X, Release 6) is >= 0.90: supports.
https://w3id.org/delphi/resource/assessment/morgan1915-04--claim-test
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true
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Dataset: FlyBase precomputed gene map table FB2026_03 (D. melanogaster Release 6 coordinates)
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