https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE/Head https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE http://www.nanopub.org/nschema#hasAssertion https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE/assertion https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE http://www.nanopub.org/nschema#hasProvenance https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE/provenance https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE http://www.nanopub.org/nschema#hasPublicationInfo https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE/pubinfo https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE/assertion https://w3id.org/delphi/resource/agent/delphisci-resolvability-assessor-gpt-5.6-sol-medium http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/ns/prov#SoftwareAgent https://w3id.org/delphi/resource/agent/delphisci-resolvability-assessor-gpt-5.6-sol-medium http://www.w3.org/2000/01/rdf-schema#label delphisci dataset-resolvability assessor (GPT-5.6 Sol) https://w3id.org/delphi/resource/agent/delphisci-resolvability-assessor-gpt-5.6-sol-medium http://www.w3.org/ns/prov#actedOnBehalfOf https://orcid.org/0009-0007-4948-9192 https://w3id.org/delphi/resource/agent/delphisci-resolvability-assessor-gpt-5.6-sol-medium https://w3id.org/delphi/ontology/usesModel https://w3id.org/delphi/resource/model/gpt-5.6-sol-medium https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt http://purl.org/dc/terms/description Parts of the proposed response can be sought in public perturbational expression data, making the claim more than purely conceptual. Those data would test only proxies for a temporally ordered autocrine-paracrine cascade and would not establish that the mechanism is critical in angiogenesis generally. The causal breadth therefore remains unresolved without additional matched perturbation data. https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt http://purl.org/dc/terms/subject https://w3id.org/delphi/resource/concept/dataset-resolvability-0.2.0 https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt http://www.w3.org/1999/02/22-rdf-syntax-ns#type https://w3id.org/delphi/ontology/LLMClaimAssessment https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt http://www.w3.org/2000/01/rdf-schema#comment Proposed test with existing data: Use matched cyclic-strain perturbation data to reconstruct the temporal sequence of endothelial autocrine responses, smooth-muscle paracrine responses, and angiogenic phenotypes, then test whether blocking proposed mediators interrupts downstream events. Failure to observe ordered signalling or persistence after blockade would refute the specified cascade. https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt http://www.w3.org/2000/01/rdf-schema#label GPT-5.6 Sol on buehler-2009-angiogenesis-03: partially-resolvable, resolvability 0.48 https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt http://www.w3.org/ns/prov#wasAttributedTo https://w3id.org/delphi/resource/agent/delphisci-resolvability-assessor-gpt-5.6-sol-medium https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt https://w3id.org/delphi/ontology/assessmentType dataset-resolvability/0.2.0 https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt https://w3id.org/delphi/ontology/evidenceAgainst Critical to angiogenesis is broader than the in vitro model. https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt https://w3id.org/delphi/ontology/evidenceAgainst Expression measurements alone cannot establish secretion or cell-cell causality. https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt https://w3id.org/delphi/ontology/evidenceAgainst Matched temporal and inhibitor data may be absent. https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt https://w3id.org/delphi/ontology/hasConfidence 0.68 https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt https://w3id.org/delphi/ontology/hasEvidence https://w3id.org/delphi/resource/evidence/buehler-2009-angiogenesis-03--gpt--dataset-1 https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt https://w3id.org/delphi/ontology/hasScore 0.481 https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt https://w3id.org/delphi/ontology/hasVerdict partially-resolvable https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--analysis-feasibility http://purl.org/dc/terms/isPartOf https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--analysis-feasibility http://purl.org/dc/terms/subject https://w3id.org/delphi/resource/concept/dataset-resolvability-0.2.0-analysis-feasibility https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--analysis-feasibility http://www.w3.org/1999/02/22-rdf-syntax-ns#type https://w3id.org/delphi/ontology/LLMClaimAssessment https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--analysis-feasibility http://www.w3.org/2000/01/rdf-schema#label Analysis feasibility of buehler-2009-angiogenesis-03 by GPT-5.6 Sol: 0.48 https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--analysis-feasibility http://www.w3.org/ns/prov#wasAttributedTo https://w3id.org/delphi/resource/agent/delphisci-resolvability-assessor-gpt-5.6-sol-medium https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--analysis-feasibility https://w3id.org/delphi/ontology/assessmentType dataset-resolvability/0.2.0/analysis-feasibility https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--analysis-feasibility https://w3id.org/delphi/ontology/hasScore 0.48 https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--data-adequacy http://purl.org/dc/terms/isPartOf https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--data-adequacy http://purl.org/dc/terms/subject https://w3id.org/delphi/resource/concept/dataset-resolvability-0.2.0-data-adequacy https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--data-adequacy http://www.w3.org/1999/02/22-rdf-syntax-ns#type https://w3id.org/delphi/ontology/LLMClaimAssessment https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--data-adequacy http://www.w3.org/2000/01/rdf-schema#label Data adequacy of buehler-2009-angiogenesis-03 by GPT-5.6 Sol: 0.25 https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--data-adequacy http://www.w3.org/ns/prov#wasAttributedTo https://w3id.org/delphi/resource/agent/delphisci-resolvability-assessor-gpt-5.6-sol-medium https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--data-adequacy https://w3id.org/delphi/ontology/assessmentType dataset-resolvability/0.2.0/data-adequacy https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--data-adequacy https://w3id.org/delphi/ontology/hasScore 0.25 https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--data-existence http://purl.org/dc/terms/isPartOf https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--data-existence http://purl.org/dc/terms/subject https://w3id.org/delphi/resource/concept/dataset-resolvability-0.2.0-data-existence https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--data-existence http://www.w3.org/1999/02/22-rdf-syntax-ns#type https://w3id.org/delphi/ontology/LLMClaimAssessment https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--data-existence http://www.w3.org/2000/01/rdf-schema#label Data existence of buehler-2009-angiogenesis-03 by GPT-5.6 Sol: 0.38 https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--data-existence http://www.w3.org/ns/prov#wasAttributedTo https://w3id.org/delphi/resource/agent/delphisci-resolvability-assessor-gpt-5.6-sol-medium https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--data-existence https://w3id.org/delphi/ontology/assessmentType dataset-resolvability/0.2.0/data-existence https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--data-existence https://w3id.org/delphi/ontology/hasScore 0.38 https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--discriminating-power http://purl.org/dc/terms/isPartOf https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--discriminating-power http://purl.org/dc/terms/subject https://w3id.org/delphi/resource/concept/dataset-resolvability-0.2.0-discriminating-power https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--discriminating-power http://www.w3.org/1999/02/22-rdf-syntax-ns#type https://w3id.org/delphi/ontology/LLMClaimAssessment https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--discriminating-power http://www.w3.org/2000/01/rdf-schema#label Discriminating power of buehler-2009-angiogenesis-03 by GPT-5.6 Sol: 0.62 https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--discriminating-power http://www.w3.org/ns/prov#wasAttributedTo https://w3id.org/delphi/resource/agent/delphisci-resolvability-assessor-gpt-5.6-sol-medium https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--discriminating-power https://w3id.org/delphi/ontology/assessmentType dataset-resolvability/0.2.0/discriminating-power https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--discriminating-power https://w3id.org/delphi/ontology/hasScore 0.62 https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--operationalizability http://purl.org/dc/terms/isPartOf https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--operationalizability http://purl.org/dc/terms/subject https://w3id.org/delphi/resource/concept/dataset-resolvability-0.2.0-operationalizability https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--operationalizability http://www.w3.org/1999/02/22-rdf-syntax-ns#type https://w3id.org/delphi/ontology/LLMClaimAssessment https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--operationalizability http://www.w3.org/2000/01/rdf-schema#label Operationalizability of buehler-2009-angiogenesis-03 by GPT-5.6 Sol: 0.7 https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--operationalizability http://www.w3.org/ns/prov#wasAttributedTo https://w3id.org/delphi/resource/agent/delphisci-resolvability-assessor-gpt-5.6-sol-medium https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--operationalizability https://w3id.org/delphi/ontology/assessmentType dataset-resolvability/0.2.0/operationalizability https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--operationalizability https://w3id.org/delphi/ontology/hasScore 0.7 https://w3id.org/delphi/resource/claim/buehler-2009-angiogenesis-03 https://w3id.org/delphi/ontology/hasAssessment https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt https://w3id.org/delphi/resource/claim/buehler-2009-angiogenesis-03 https://w3id.org/delphi/ontology/hasAssessment https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--analysis-feasibility https://w3id.org/delphi/resource/claim/buehler-2009-angiogenesis-03 https://w3id.org/delphi/ontology/hasAssessment https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--data-adequacy https://w3id.org/delphi/resource/claim/buehler-2009-angiogenesis-03 https://w3id.org/delphi/ontology/hasAssessment https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--data-existence https://w3id.org/delphi/resource/claim/buehler-2009-angiogenesis-03 https://w3id.org/delphi/ontology/hasAssessment https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--discriminating-power https://w3id.org/delphi/resource/claim/buehler-2009-angiogenesis-03 https://w3id.org/delphi/ontology/hasAssessment https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt--operationalizability https://w3id.org/delphi/resource/evidence/buehler-2009-angiogenesis-03--gpt--dataset-1 http://purl.org/dc/terms/description public expression studies for testing parts of the cellular response to mechanical strain https://w3id.org/delphi/resource/evidence/buehler-2009-angiogenesis-03--gpt--dataset-1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type https://w3id.org/delphi/ontology/EvidenceItem https://w3id.org/delphi/resource/evidence/buehler-2009-angiogenesis-03--gpt--dataset-1 http://www.w3.org/2000/01/rdf-schema#label Candidate dataset: NCBI Gene Expression Omnibus https://w3id.org/delphi/resource/evidence/buehler-2009-angiogenesis-03--gpt--dataset-1 http://www.w3.org/ns/prov#wasDerivedFrom https://www.ncbi.nlm.nih.gov/geo/ https://w3id.org/delphi/resource/model/gpt-5.6-sol-medium http://purl.org/dc/terms/identifier gpt-5.6-sol-medium https://w3id.org/delphi/resource/model/gpt-5.6-sol-medium http://www.w3.org/1999/02/22-rdf-syntax-ns#type https://w3id.org/delphi/ontology/LanguageModel https://w3id.org/delphi/resource/model/gpt-5.6-sol-medium http://www.w3.org/2000/01/rdf-schema#label GPT-5.6 Sol https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE/provenance https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE/assertion http://www.w3.org/ns/prov#wasAttributedTo https://w3id.org/delphi/resource/agent/delphisci-resolvability-assessor-gpt-5.6-sol-medium https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE/assertion http://www.w3.org/ns/prov#wasDerivedFrom https://github.com/fractastical/delphisci/blob/67fe5b156cfeca15a2ded33e0face4177d03101c/claim-sources/buehler-protein-materials/assessment/raw/gpt/batch-4.json https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE/assertion http://www.w3.org/ns/prov#wasDerivedFrom https://w3id.org/delphi/resource/concept/dataset-resolvability-0.2.0 https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE/assertion http://www.w3.org/ns/prov#wasGeneratedBy https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE/assessment https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE/assessment http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/ns/prov#Activity https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE/assessment http://www.w3.org/ns/prov#qualifiedAssociation https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE/assessmentPlan https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE/assessment http://www.w3.org/ns/prov#wasAssociatedWith https://w3id.org/delphi/resource/agent/delphisci-resolvability-assessor-gpt-5.6-sol-medium https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE/assessmentPlan http://www.w3.org/ns/prov#hadPlan https://github.com/fractastical/delphisci/blob/67fe5b156cfeca15a2ded33e0face4177d03101c/claim-sources/buehler-protein-materials/README.md https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE/pubinfo https://w3id.org/delphi/resource/domain/buehler-protein-materials http://www.w3.org/2000/01/rdf-schema#label buehler-protein-materials https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE http://purl.org/dc/terms/created 2026-11-08T04:48:50.317Z https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE http://purl.org/dc/terms/creator https://orcid.org/0009-0007-4948-9192 https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE http://purl.org/dc/terms/license https://creativecommons.org/licenses/by/4.0/ https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE http://purl.org/nanopub/x/hasNanopubType https://w3id.org/delphi/ontology/LLMClaimAssessment https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE http://purl.org/nanopub/x/introduces https://w3id.org/delphi/resource/assessment/buehler-2009-angiogenesis-03--gpt https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE http://www.w3.org/2000/01/rdf-schema#label GPT-5.6 Sol on buehler-2009-angiogenesis-03: partially-resolvable, resolvability 0.48 https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE https://w3id.org/delphi/ontology/domain https://w3id.org/delphi/resource/domain/buehler-protein-materials https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE/sig http://purl.org/nanopub/x/hasAlgorithm RSA https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE/sig http://purl.org/nanopub/x/hasPublicKey MIIBIjANBgkqhkiG9w0BAQEFAAOCAQ8AMIIBCgKCAQEAyFHtPB6p0mCjDozxlOY9CmO3nBm7Te3jFbXyLmM+G1tGe47Da0jYIbhkl9Oo1ZjxmCa3LCwlEqK8gj6hEIcL4ahW30JXh9HycfKVk1bugkzMEV15tJdTzAU3sGMFnbNsn43xY2LFLy45tApkRm5byEiM7oRRrooIdwoQKnP4Wzq/bfAoJ9qvW+MGkelyOTd1jbSt+KfmT7xKmDfWzAHddUlWwMX2QJOLxDaffOteTop6ZRgPiNmPJKA/S62Gac9XtSYT3oDkZ6/nr5cxxNLpOyxTf5FPISiCe11xYO/unYjY+mwnOfA8yhJIyx1l0O9I0vpOpn+E5TvyHJV+oSTrvwIDAQAB https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE/sig http://purl.org/nanopub/x/hasSignature n11e0GnGPSklrTZ+523Q6La8Wfcg3PSukLixIcG54CGZHOfnjXGZdLl07ZajjRe9ehXvo4YZVS77m/19MV2NmJWWl+mK27tkVe/jEd6g2ZI2oY9HJ5oqo3pkAvCZt1/xTLTfCnMSuQDiMKfdKQHGgRFwPA1nQsyBLTefM22s3N1lDH65E0nUJchD4Orb3oooptVT2kRaizcrWhcvfzhzDFleYjhGWNbsv3iUyjLej3NtcsYPgvGN0F7e17gD3rzuBgYCmAy5PLsogfhOeIW0Gxk8EaGPhvrC2rnw+qtquF6BURq4e/gNIvPfgrAJp6+VvrfdZ0JtXrPgxxZzg3M7fQ== https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE/sig http://purl.org/nanopub/x/hasSignatureTarget https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE https://w3id.org/np/RAcco8rGC5LVXB_OHsdFJeuOHOBV8m7yOfOzEitNxqZOE/sig http://purl.org/nanopub/x/signedBy https://orcid.org/0009-0007-4948-9192