. . . . . "delphisci dataset-resolvability assessor (GPT-5.6 Sol)" . . . "Parts of the proposed response can be sought in public perturbational expression data, making the claim more than purely conceptual. Those data would test only proxies for a temporally ordered autocrine-paracrine cascade and would not establish that the mechanism is critical in angiogenesis generally. The causal breadth therefore remains unresolved without additional matched perturbation data." . . . "Proposed test with existing data: Use matched cyclic-strain perturbation data to reconstruct the temporal sequence of endothelial autocrine responses, smooth-muscle paracrine responses, and angiogenic phenotypes, then test whether blocking proposed mediators interrupts downstream events. Failure to observe ordered signalling or persistence after blockade would refute the specified cascade." . "GPT-5.6 Sol on buehler-2009-angiogenesis-03: partially-resolvable, resolvability 0.48" . . "dataset-resolvability/0.2.0" . "Critical to angiogenesis is broader than the in vitro model." . "Expression measurements alone cannot establish secretion or cell-cell causality." . "Matched temporal and inhibitor data may be absent." . "0.68"^^ . . "0.481"^^ . "partially-resolvable" . . . . "Analysis feasibility of buehler-2009-angiogenesis-03 by GPT-5.6 Sol: 0.48" . . "dataset-resolvability/0.2.0/analysis-feasibility" . "0.48"^^ . . . . "Data adequacy of buehler-2009-angiogenesis-03 by GPT-5.6 Sol: 0.25" . . "dataset-resolvability/0.2.0/data-adequacy" . "0.25"^^ . . . . "Data existence of buehler-2009-angiogenesis-03 by GPT-5.6 Sol: 0.38" . . "dataset-resolvability/0.2.0/data-existence" . "0.38"^^ . . . . "Discriminating power of buehler-2009-angiogenesis-03 by GPT-5.6 Sol: 0.62" . . "dataset-resolvability/0.2.0/discriminating-power" . "0.62"^^ . . . . "Operationalizability of buehler-2009-angiogenesis-03 by GPT-5.6 Sol: 0.7" . . "dataset-resolvability/0.2.0/operationalizability" . "0.7"^^ . . . . . . . "public expression studies for testing parts of the cellular response to mechanical strain" . . "Candidate dataset: NCBI Gene Expression Omnibus" . . "gpt-5.6-sol-medium" . . "GPT-5.6 Sol" . . . . . . . . . "buehler-protein-materials" . "2026-11-08T04:48:50.317Z"^^ . . . . . "GPT-5.6 Sol on buehler-2009-angiogenesis-03: partially-resolvable, resolvability 0.48" . . "RSA" . "MIIBIjANBgkqhkiG9w0BAQEFAAOCAQ8AMIIBCgKCAQEAyFHtPB6p0mCjDozxlOY9CmO3nBm7Te3jFbXyLmM+G1tGe47Da0jYIbhkl9Oo1ZjxmCa3LCwlEqK8gj6hEIcL4ahW30JXh9HycfKVk1bugkzMEV15tJdTzAU3sGMFnbNsn43xY2LFLy45tApkRm5byEiM7oRRrooIdwoQKnP4Wzq/bfAoJ9qvW+MGkelyOTd1jbSt+KfmT7xKmDfWzAHddUlWwMX2QJOLxDaffOteTop6ZRgPiNmPJKA/S62Gac9XtSYT3oDkZ6/nr5cxxNLpOyxTf5FPISiCe11xYO/unYjY+mwnOfA8yhJIyx1l0O9I0vpOpn+E5TvyHJV+oSTrvwIDAQAB" . "n11e0GnGPSklrTZ+523Q6La8Wfcg3PSukLixIcG54CGZHOfnjXGZdLl07ZajjRe9ehXvo4YZVS77m/19MV2NmJWWl+mK27tkVe/jEd6g2ZI2oY9HJ5oqo3pkAvCZt1/xTLTfCnMSuQDiMKfdKQHGgRFwPA1nQsyBLTefM22s3N1lDH65E0nUJchD4Orb3oooptVT2kRaizcrWhcvfzhzDFleYjhGWNbsv3iUyjLej3NtcsYPgvGN0F7e17gD3rzuBgYCmAy5PLsogfhOeIW0Gxk8EaGPhvrC2rnw+qtquF6BURq4e/gNIvPfgrAJp6+VvrfdZ0JtXrPgxxZzg3M7fQ==" . . .