@prefix this: . @prefix sub: . @prefix np: . @prefix rdf: . @prefix prov: . @prefix npx: . @prefix dc: . @prefix xsd: . sub:Head { this: a np:Nanopublication; np:hasAssertion sub:assertion; np:hasProvenance sub:provenance; np:hasPublicationInfo sub:pubinfo . } sub:assertion { a ; dc:description "Cyclic tensile strain of human umbilical vein endothelial cells up-regulates secretion of angiopoietin-2 and PDGF-BB and enhances endothelial migration and sprout formation; these effects disappear when endogenous Ang-2 is knocked down by shRNA."; dc:type "experimental-result"; "Cyclic strain of endothelial cells raises Ang-2 and PDGF-BB secretion and drives sprouting"; "Yu Ching Yung et al., “Cyclic tensile strain triggers a sequence of autocrine and paracrine signaling to regulate angiogenic sprouting in human vascular cells”, Proceedings of the National Academy of Sciences 106, 15279-15284 (2009), doi:10.1073/pnas.0905891106; Abstract. Scope: HUVECs under cyclic tensile strain in vitro" . } sub:provenance { a ; dc:bibliographicCitation "Yu Ching Yung, Jeiwook Chae, Markus J. Buehler, Craig P. Hunter, David J. Mooney. Cyclic tensile strain triggers a sequence of autocrine and paracrine signaling to regulate angiogenic sprouting in human vascular cells. Proceedings of the National Academy of Sciences 106, 15279-15284 (2009). doi:10.1073/pnas.0905891106"; dc:creator "Yu Ching Yung, Jeiwook Chae, Markus J. Buehler, Craig P. Hunter, David J. Mooney"; dc:date "2009"^^xsd:gYear; dc:identifier "PMC2741242", "doi:10.1073/pnas.0905891106", "pmid:19706407"; dc:title "Cyclic tensile strain triggers a sequence of autocrine and paracrine signaling to regulate angiogenic sprouting in human vascular cells" . a prov:SoftwareAgent; "delphisci buehler-protein-materials claim extractor"; prov:actedOnBehalfOf ; . a ; "Claude Fable 5.1" . sub:assertion prov:wasAttributedTo ; prov:wasDerivedFrom , sub:quote; prov:wasGeneratedBy sub:extraction . sub:extraction a prov:Activity; prov:qualifiedAssociation sub:extractionPlan; prov:used , ; prov:wasAssociatedWith . sub:extractionPlan prov:hadPlan . sub:quote a prov:Entity; "Quoted from the published abstract as returned by Europe PMC (2009-angiogenesis.abstract.txt, sha256 a9912c839d3da8e9872e3ae20abe855f3ab1a6790a8ce7381466b7561048c712); the full text was not read (not in Europe PMC open-access subset). Checked by build/check.py."; prov:hadPrimarySource ; prov:wasQuotedFrom ; "Cyclic strain of human umbilical vein (HUV)ECs up-regulated the secretion of angiopoietin (Ang)-2 and PDGF-betabeta, and enhanced endothelial migration and sprout formation, whereas effects were eliminated with shRNA knockdown of endogenous Ang-2." . sub:sourceChecksum ; "a9912c839d3da8e9872e3ae20abe855f3ab1a6790a8ce7381466b7561048c712"; "Checksum of the vendored text file inputs/2009-angiogenesis.abstract.txt, not of the publisher's copy." . a prov:Entity; sub:sourceChecksum; "Abstract of Cyclic tensile strain triggers a sequence of autocrine and paracrine signaling to regulate angiogenic sprouting in human vascular cells, as read"; . } sub:pubinfo { "buehler-protein-materials" . this: dc:created "2026-11-08T04:38:11.893Z"^^xsd:dateTime; dc:creator ; dc:license ; npx:hasNanopubType ; npx:introduces ; "Yu Ching Yung et al. 2009 claim: Cyclic strain of endothelial cells raises Ang-2 and PDGF-BB secretion and drives sprouting"; . sub:sig npx:hasAlgorithm "RSA"; npx:hasPublicKey "MIIBIjANBgkqhkiG9w0BAQEFAAOCAQ8AMIIBCgKCAQEAyFHtPB6p0mCjDozxlOY9CmO3nBm7Te3jFbXyLmM+G1tGe47Da0jYIbhkl9Oo1ZjxmCa3LCwlEqK8gj6hEIcL4ahW30JXh9HycfKVk1bugkzMEV15tJdTzAU3sGMFnbNsn43xY2LFLy45tApkRm5byEiM7oRRrooIdwoQKnP4Wzq/bfAoJ9qvW+MGkelyOTd1jbSt+KfmT7xKmDfWzAHddUlWwMX2QJOLxDaffOteTop6ZRgPiNmPJKA/S62Gac9XtSYT3oDkZ6/nr5cxxNLpOyxTf5FPISiCe11xYO/unYjY+mwnOfA8yhJIyx1l0O9I0vpOpn+E5TvyHJV+oSTrvwIDAQAB"; npx:hasSignature "W0l5w/nq3aRUZQGe+7DK1Yuff7LBRAgxXmkYK4EYP3NJwdnketHZHuMm0O3gOlj8KIdXatNtShmIVK4WGFPA42AGUBR3ZSIBY1Aavs86Ecwgj8GoKmx2slTIe8pYlGouIySys/8S7NNGLFR+IXA8bCQLXRUclEgXKWlqxyr9+2SgKQ8yh1DkZcdMvcdvd4zG0fDlL3DprbO7cvjON3QXPEKHYtFCNM16b9XUMHqvy4x2tWHi41Oi0Ta/BlLfoEDkyw8wPDDril1K/pQGbGMOfxsO/C+7+lmuNANybnixNy+58BpklE5HZlpK9kzZaDC/RzAZTAn89PhyLWycJQ55VA=="; npx:hasSignatureTarget this:; npx:signedBy . }