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The repository contains MEMORY_EVALUATOR_ODE_SLURM1_Noise.m and no output matrix of that noise assay. The ODE right-hand sides are absent, so the noise comparison was not re-run.
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Measured: null null. Interpretation: Noise here is noise added inside the ODE simulations. The result does not show that biological noise helps memory in cells. data_kind will be computational.
https://w3id.org/delphi/resource/assessment/levin-2022-grn-learning-10--claim-test
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Claim test of levin-2022-grn-learning-10: inconclusive, confidence 0.35
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The same published ODE models used for the noiseless memory assay, re-integrated with a stated stochastic perturbation. A typed copy of the paper's 83% and 20% is not admissible.
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Fewer than 83% of those models keep a memory, or mean memory amount falls when noise is added.
https://w3id.org/delphi/resource/assessment/levin-2022-grn-learning-10--claim-test
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The noise script is present and its output matrix is not. Intact-fraction and the 20% increase were not measured.
https://w3id.org/delphi/resource/assessment/levin-2022-grn-learning-10--claim-test
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At least 83% of models that had a memory without noise still have one with noise, and mean memory amount rises by a relative factor between 10% and 30%.
https://w3id.org/delphi/resource/assessment/levin-2022-grn-learning-10--claim-test
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Refutes if the intact fraction is < 0.83, or if the relative increase is negative. Mixed if the intact fraction is >= 0.83 but the relative increase is outside [0.10, 0.30] while still non-negative. Inconclusive with reason underpowered if fewer than 10 models have memory without noise. Inconclusive with reason data-unavailable if the models cannot be fetched.
https://w3id.org/delphi/resource/assessment/levin-2022-grn-learning-10--claim-test
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Stochastic noise leaves memories intact in at least 83% of the pathway models that had memory, and increases memory amount overall by about 20%.
https://w3id.org/delphi/resource/assessment/levin-2022-grn-learning-10--claim-test
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Paired comparison of memory labels and memory amount with and without noise. Intact fraction against 0.83; relative change of the mean against the interval [0.10, 0.30]. Both bars are required for supports.
https://w3id.org/delphi/resource/assessment/levin-2022-grn-learning-10--claim-test
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Pre-registered before any model file or simulation output is downloaded. The pass bars are the fractions stated in the claim. Intact: among models that have at least one memory kind without noise, the fraction that still have at least one memory kind when stochastic noise is added is >= 0.83. Increase: (mean memory amount with noise minus mean memory amount without noise) divided by mean memory amount without noise, over those models, is about 20%, fixed here as the closed interval from 0.10 to 0.30. Memory amount and memory kinds are those in the levin-2022-grn-learning-01 preregistration. Noise is the stochastic term in the authors' GRN_ODE noise assay if that code runs; otherwise independent multiplicative log-normal noise on production rates with sigma fixed in the analysis script before any noisy trajectory is scored. Supports only if both the intact bar and the increase interval hold.
https://w3id.org/delphi/resource/assessment/levin-2022-grn-learning-10--claim-test
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authors' MATLAB sources and deposited simulation-count matrices; the ODE right-hand sides are not in this repository
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Dataset: Table S1, list of 35 BioModels ODE networks
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