https://w3id.org/np/RAIWBZOchcwtSMnhae6v09ZWhX47-JgjXWJXd0Ps801rw/Head https://w3id.org/np/RAIWBZOchcwtSMnhae6v09ZWhX47-JgjXWJXd0Ps801rw http://www.nanopub.org/nschema#hasAssertion https://w3id.org/np/RAIWBZOchcwtSMnhae6v09ZWhX47-JgjXWJXd0Ps801rw/assertion https://w3id.org/np/RAIWBZOchcwtSMnhae6v09ZWhX47-JgjXWJXd0Ps801rw http://www.nanopub.org/nschema#hasProvenance https://w3id.org/np/RAIWBZOchcwtSMnhae6v09ZWhX47-JgjXWJXd0Ps801rw/provenance https://w3id.org/np/RAIWBZOchcwtSMnhae6v09ZWhX47-JgjXWJXd0Ps801rw http://www.nanopub.org/nschema#hasPublicationInfo https://w3id.org/np/RAIWBZOchcwtSMnhae6v09ZWhX47-JgjXWJXd0Ps801rw/pubinfo https://w3id.org/np/RAIWBZOchcwtSMnhae6v09ZWhX47-JgjXWJXd0Ps801rw http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication https://w3id.org/np/RAIWBZOchcwtSMnhae6v09ZWhX47-JgjXWJXd0Ps801rw/assertion https://w3id.org/delphi/resource/claim/buehler-2009-angiogenesis-02 http://purl.org/dc/terms/description Straining HUVEC colonies co-cultured on a micropatterned substrate with unstrained human aortic smooth muscle cells directs the smooth muscle cells to migrate toward the migrating endothelial cells, and recruitment falls when PDGF receptors are neutralised. https://w3id.org/delphi/resource/claim/buehler-2009-angiogenesis-02 http://purl.org/dc/terms/type experimental-result https://w3id.org/delphi/resource/claim/buehler-2009-angiogenesis-02 http://www.w3.org/1999/02/22-rdf-syntax-ns#type https://w3id.org/delphi/ontology/Claim https://w3id.org/delphi/resource/claim/buehler-2009-angiogenesis-02 http://www.w3.org/2000/01/rdf-schema#label Strained endothelial colonies recruit unstrained smooth muscle cells through PDGF receptors https://w3id.org/delphi/resource/claim/buehler-2009-angiogenesis-02 https://w3id.org/delphi/ontology/context Yu Ching Yung et al., “Cyclic tensile strain triggers a sequence of autocrine and paracrine signaling to regulate angiogenic sprouting in human vascular cells”, Proceedings of the National Academy of Sciences 106, 15279-15284 (2009), doi:10.1073/pnas.0905891106; Abstract. Scope: HUVEC–HASMC co-culture on micropatterned substrates https://w3id.org/np/RAIWBZOchcwtSMnhae6v09ZWhX47-JgjXWJXd0Ps801rw/provenance https://doi.org/10.1073/pnas.0905891106 http://purl.org/dc/terms/bibliographicCitation Yu Ching Yung, Jeiwook Chae, Markus J. Buehler, Craig P. Hunter, David J. Mooney. Cyclic tensile strain triggers a sequence of autocrine and paracrine signaling to regulate angiogenic sprouting in human vascular cells. Proceedings of the National Academy of Sciences 106, 15279-15284 (2009). doi:10.1073/pnas.0905891106 https://doi.org/10.1073/pnas.0905891106 http://purl.org/dc/terms/creator Yu Ching Yung, Jeiwook Chae, Markus J. Buehler, Craig P. Hunter, David J. 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Checked by build/check.py. https://w3id.org/np/RAIWBZOchcwtSMnhae6v09ZWhX47-JgjXWJXd0Ps801rw/quote http://www.w3.org/ns/prov#hadPrimarySource https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=DOI:10.1073/pnas.0905891106&resultType=core&format=json https://w3id.org/np/RAIWBZOchcwtSMnhae6v09ZWhX47-JgjXWJXd0Ps801rw/quote http://www.w3.org/ns/prov#wasQuotedFrom https://doi.org/10.1073/pnas.0905891106 https://w3id.org/np/RAIWBZOchcwtSMnhae6v09ZWhX47-JgjXWJXd0Ps801rw/quote https://schema.org/text Applying strain to colonies of HUVEC, cocultured on the same micropatterned substrate with nonstrained human aortic (HA)SMCs, led to a directed migration of the HASMC toward migrating HUVECs, with diminished recruitment when PDGF receptors were neutralized. https://w3id.org/np/RAIWBZOchcwtSMnhae6v09ZWhX47-JgjXWJXd0Ps801rw/sourceChecksum http://spdx.org/rdf/terms#algorithm http://spdx.org/rdf/terms#checksumAlgorithm_sha256 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