https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ/Head https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ http://www.nanopub.org/nschema#hasAssertion https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ/assertion https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ http://www.nanopub.org/nschema#hasProvenance https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ/provenance https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ http://www.nanopub.org/nschema#hasPublicationInfo https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ/pubinfo https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ/assertion https://w3id.org/delphi/resource/claim/buehler-2007-hierarchies-04 http://purl.org/dc/terms/description In the hierarchical Bell model applied to alpha-helices, 3–4 parallel hydrogen bonds per turn are optimal for the protein's combined mechanical and thermodynamic stability, matching the 3.6 hydrogen bonds per turn of real alpha-helices. https://w3id.org/delphi/resource/claim/buehler-2007-hierarchies-04 http://purl.org/dc/terms/type prediction https://w3id.org/delphi/resource/claim/buehler-2007-hierarchies-04 http://www.w3.org/1999/02/22-rdf-syntax-ns#type https://w3id.org/delphi/ontology/Claim https://w3id.org/delphi/resource/claim/buehler-2007-hierarchies-04 http://www.w3.org/2000/01/rdf-schema#comment Notation basis: The optimum and the observed value are stated in the abstract; the objective being optimised is in the full text. https://w3id.org/delphi/resource/claim/buehler-2007-hierarchies-04 http://www.w3.org/2000/01/rdf-schema#label Three to four parallel hydrogen bonds per turn is the mechanically and thermodynamically favoured number https://w3id.org/delphi/resource/claim/buehler-2007-hierarchies-04 http://www.w3.org/2004/02/skos/core#notation b^{*} \in \{3, 4\} \quad (\text{observed } b = 3.6 \text{ H-bonds per turn}) https://w3id.org/delphi/resource/claim/buehler-2007-hierarchies-04 https://w3id.org/delphi/ontology/context Theodor Ackbarow et al., “Hierarchies, multiple energy barriers, and robustness govern the fracture mechanics of α-helical and β-sheet protein domains”, Proceedings of the National Academy of Sciences 104, 16410-16415 (2007), doi:10.1073/pnas.0705759104; Abstract. Scope: Alpha-helical protein domains https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ/provenance https://doi.org/10.1073/pnas.0705759104 http://purl.org/dc/terms/bibliographicCitation Theodor Ackbarow, Xuefeng Chen, Sinan Keten, Markus J. Buehler. Hierarchies, multiple energy barriers, and robustness govern the fracture mechanics of α-helical and β-sheet protein domains. Proceedings of the National Academy of Sciences 104, 16410-16415 (2007). doi:10.1073/pnas.0705759104 https://doi.org/10.1073/pnas.0705759104 http://purl.org/dc/terms/creator Theodor Ackbarow, Xuefeng Chen, Sinan Keten, Markus J. 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Checked by build/check.py. https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ/quote http://www.w3.org/ns/prov#hadPrimarySource https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=DOI:10.1073/pnas.0705759104&resultType=core&format=json https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ/quote http://www.w3.org/ns/prov#wasQuotedFrom https://doi.org/10.1073/pnas.0705759104 https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ/quote https://schema.org/text We exemplify our model in a study of AHs, and show that 3-4 parallel HBs per turn are favorable in light of the protein's mechanical and thermodynamical stability, in agreement with experimental findings that AHs feature 3.6 HBs per turn. https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ/sourceChecksum http://spdx.org/rdf/terms#algorithm http://spdx.org/rdf/terms#checksumAlgorithm_sha256 https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ/sourceChecksum http://spdx.org/rdf/terms#checksumValue 4f052f4a8a9ddc7dfecc384493c31e0f00fcd9873ded36486b8618493fdf4e18 https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ/sourceChecksum http://www.w3.org/2000/01/rdf-schema#comment Checksum of the vendored text file inputs/2007-hierarchies.abstract.txt, not of the publisher's copy. https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=DOI:10.1073/pnas.0705759104&resultType=core&format=json http://spdx.org/rdf/terms#checksum https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ/sourceChecksum https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=DOI:10.1073/pnas.0705759104&resultType=core&format=json http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/ns/prov#Entity https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=DOI:10.1073/pnas.0705759104&resultType=core&format=json http://www.w3.org/2000/01/rdf-schema#label Abstract of Hierarchies, multiple energy barriers, and robustness govern the fracture mechanics of α-helical and β-sheet protein domains, as read https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=DOI:10.1073/pnas.0705759104&resultType=core&format=json https://schema.org/about https://doi.org/10.1073/pnas.0705759104 https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ/pubinfo https://w3id.org/delphi/resource/domain/buehler-protein-materials http://www.w3.org/2000/01/rdf-schema#label buehler-protein-materials https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ http://purl.org/dc/terms/created 2026-11-08T04:38:11.893Z https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ http://purl.org/dc/terms/creator https://orcid.org/0009-0007-4948-9192 https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ http://purl.org/dc/terms/license https://creativecommons.org/licenses/by/4.0/ https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ http://purl.org/nanopub/x/hasNanopubType https://w3id.org/delphi/ontology/Claim https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ http://purl.org/nanopub/x/introduces https://w3id.org/delphi/resource/claim/buehler-2007-hierarchies-04 https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ http://www.w3.org/2000/01/rdf-schema#label Theodor Ackbarow et al. 2007 claim: Three to four parallel hydrogen bonds per turn is the mechanically and thermodynamically favoured number https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ https://w3id.org/delphi/ontology/domain https://w3id.org/delphi/resource/domain/buehler-protein-materials https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ/sig http://purl.org/nanopub/x/hasAlgorithm RSA https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ/sig http://purl.org/nanopub/x/hasPublicKey MIIBIjANBgkqhkiG9w0BAQEFAAOCAQ8AMIIBCgKCAQEAyFHtPB6p0mCjDozxlOY9CmO3nBm7Te3jFbXyLmM+G1tGe47Da0jYIbhkl9Oo1ZjxmCa3LCwlEqK8gj6hEIcL4ahW30JXh9HycfKVk1bugkzMEV15tJdTzAU3sGMFnbNsn43xY2LFLy45tApkRm5byEiM7oRRrooIdwoQKnP4Wzq/bfAoJ9qvW+MGkelyOTd1jbSt+KfmT7xKmDfWzAHddUlWwMX2QJOLxDaffOteTop6ZRgPiNmPJKA/S62Gac9XtSYT3oDkZ6/nr5cxxNLpOyxTf5FPISiCe11xYO/unYjY+mwnOfA8yhJIyx1l0O9I0vpOpn+E5TvyHJV+oSTrvwIDAQAB https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ/sig http://purl.org/nanopub/x/hasSignature cOD+kt5F+fIj92K3/uLPBb76PGCD3fqo5sy05xiQ7QB5I69Buk+cgvt6IIUKjYmx72PPHhsvw5bV7h9dR1i6RNjXa9acfqQjnNWS6ITba49YEpnbSzf9890X0GP2q5S9l+8Hur5t3iSoJvyccrx+ENRLA9aettNyZBWy+zrkaWdngf3mFryiFL1i7t7r/tD7eAZfDx9B+za0YHcPuSzFby/SnKPSLowmHXLIFx7D7qlqlzr+SadqAO/Lx+zS5OnENQLgF7SYuVwjNDAo+qg7JflFmzAnTdsPA1K3JFRCTIFt+usWURvDN0TjcAtnvBOH0eC0IqAh0+FjfYF3XHJ0sQ== https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ/sig http://purl.org/nanopub/x/hasSignatureTarget https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ https://w3id.org/np/RABHZUUeSyiShJvoX83cMoJ8zvoemiVqEPCbWOTxV7nUQ/sig http://purl.org/nanopub/x/signedBy https://orcid.org/0009-0007-4948-9192